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৩২ নং লাইন:
Whooping cough, also called pertussis, is a contagious disease that affects the [[respiratory tract]]. The infection is caused by a bacterium that sticks to the cilia of the upper respiratory tract and can be very contagious. Pertussis can be especially dangerous for babies, whose immune system are not yet fully developed, and can develop into [[pneumonia]] or result in the baby having trouble breathing.<ref>{{Cite web|title = Pertussis {{!}} Whooping Cough {{!}} Complications {{!}} CDC|url = https://www.cdc.gov/pertussis/about/complications.html|website = www.cdc.gov|access-date = 2016-02-16}}</ref> [[DPT vaccine|DTaP]] is the primary vaccine given against pertussis, and children typically receive five doses before the age of seven. Tdap is the booster for pertussis, and is advised in the US to be administered every ten years, and during every pregnancy for mothers. Tdap can also be used as a booster against tetanus.<ref>{{Cite web|title = Vaccines: VPD-VAC/Pertussis/main page|url = https://www.cdc.gov/vaccines/vpd-vac/pertussis/default.htm?s_cid=cs_074|website = www.cdc.gov|access-date = 2016-02-16}}</ref>
Upon its invention in the 1950s, the pertussis vaccine was whole-cell (contained the entire inactivated bacterium), and could cause fever and local reactions in people who received the vaccine. In the 1990s, people in the US started using acellular vaccines (contained small portions of the bacterium), that had lower side effects but were also less effective at triggering an immunological memory response, due to the antigen presented to the immune system being less complete.<ref>{{Cite journal|title = Whooping Cough in 2014 and Beyond: An Update and Review|url = https://archive.org/details/sim_chest_2014-07_146_1/page/205|journal = Chest|date = 2014-07-01|pages = 205–214|volume = 146|issue = 1|doi = 10.1378/chest.13-2942|first1 = Joshua D.|last1 = Hartzell|first2 = Jason M.|last2 = Blaylock|pmid=25010963}}</ref> This less effective, but safer vaccine, led to the development of the booster Tdap.
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===কোভিড-১৯ টিকার গুণবর্ধক মাত্রা===
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